Menopause is a natural transition in every woman’s life, but it often brings along uncomfortable symptoms such as weight gain, mood swings, fatigue, and hormonal imbalance. These changes usually happen because the body’s production of estrogen and progesterone begins to decline, affecting metabolism, mood regulation, and overall energy levels.
While lifestyle habits like eating healthy and exercising regularly can help, many women still struggle with these symptoms. That’s where menopause supplements come in — they are designed to support hormone balance, reduce mood fluctuations, and help manage menopausal weight gain naturally.
In this detailed 2025 guide, we’ll explore the best menopause supplements for weight gain and mood swings, review top products, and help you understand how to choose one that truly works for your body.
By the end of this article, you’ll know which supplements can:
- Support hormonal balance
- Help manage menopause-related weight gain
- Improve mood, sleep, and energy
- And offer safe, natural relief without synthetic hormones
Let’s start by taking a quick look at the top-rated menopause supplements of 2025 that are trusted by women worldwide.
Quick Verdict: Top 3 Menopause Supplements for Weight Gain & Mood Swings (2025)
Choosing the right menopause supplement can make a huge difference in how you manage weight gain, mood swings, and hormonal imbalance. After reviewing dozens of products, we’ve narrowed down the top three formulas that offer natural hormone support, mood balance, and metabolism benefits — all backed by positive customer reviews and scientific ingredients.
| Rank | Supplement | Key Benefits | Ideal For | Rating |
| 1 | Estroven Weight Management | Combines soy isoflavones, black cohosh, and green tea extract to support metabolism, reduce hot flashes, and ease mood fluctuations. | Women struggling with belly fat and emotional instability during menopause. | ⭐⭐⭐⭐⭐ (4.8/5) |
| 2 | Bonafide Serenol | A plant-based supplement designed to relieve irritability, anxiety, and mood swings caused by hormonal changes. Contains chromium picolinate for appetite control. | Women seeking calmness, emotional balance, and better appetite regulation. | ⭐⭐⭐⭐☆ (4.6/5) |
| 3 | New Chapter Estrotone | Features evening primrose oil, black cohosh, and chaste tree to promote hormone balance and reduce bloating. Free from synthetic hormones. | Women preferring herbal menopause support for both mood and metabolism. | ⭐⭐⭐⭐☆ (4.5/5) |
Editor’s Choice:
For women struggling with both menopause weight gain and mood swings, Estroven Weight Management delivers the best all-round support — balancing hormones naturally and helping improve metabolism and emotional stability.
What Causes Weight Gain and Mood Swings During Menopause?
Menopause marks the end of a woman’s reproductive years and usually occurs between ages 45 to 55. During this transition, the body goes through major hormonal shifts — especially a drop in estrogen and progesterone levels. These hormonal changes affect everything from metabolism to mental well-being.

1. Hormonal Imbalance Slows Metabolism
Estrogen helps regulate how your body stores fat. When estrogen levels fall, your body tends to store more fat around the abdomen, leading to what’s often called “menopause belly.”
This change in metabolism makes it harder to maintain or lose weight, even if your diet and activity levels stay the same.
2. Changes in Mood and Emotional Health
Fluctuating hormones also influence serotonin, a neurotransmitter that affects mood. As serotonin levels dip, many women experience:
- Increased irritability
- Anxiety or restlessness
- Low motivation
- Sudden mood swings
This emotional instability can lead to stress eating or loss of motivation to exercise, further contributing to weight gain.
3. Poor Sleep and Fatigue
Menopause often brings night sweats and insomnia, leading to chronic fatigue. When you’re tired, your body releases more cortisol, the stress hormone that promotes fat storage and mood imbalance.
4. Reduced Muscle Mass
With age and hormonal decline, muscle mass naturally decreases. Since muscle burns more calories than fat, reduced muscle mass means a slower metabolism and easier weight gain.
How Supplements Help in Menopause Weight and Mood Management
Menopause supplements are designed to restore hormonal balance and reduce the uncomfortable symptoms that occur during this stage of life. The best menopause supplements for weight gain and mood swings contain a blend of vitamins, minerals, and herbal ingredients that work naturally with your body’s chemistry.
Let’s understand how they help in detail.
1. Balancing Estrogen Levels Naturally
A major cause of menopause symptoms is declining estrogen. Natural compounds like soy isoflavones, red clover, and black cohosh act as phytoestrogens — plant-based ingredients that mimic estrogen’s effects.
They help:
- Reduce hot flashes and night sweats
- Maintain hormonal equilibrium
- Support mood stability and energy
These ingredients don’t contain artificial hormones, making them a safe choice for long-term use.
2. Supporting Metabolism and Weight Control
Supplements that include green tea extract, chromium picolinate, or maca root can help improve metabolism and reduce fat storage.
They work by:
- Enhancing fat oxidation
- Stabilizing blood sugar levels
- Preventing cravings and overeating
- Increasing energy levels for daily activity
This helps women manage menopause-related belly fat and maintain a healthy weight even with slower metabolism.
3. Reducing Stress and Mood Swings
Adaptogenic herbs such as ashwagandha, rhodiola, and chaste tree extract help your body adapt to stress.
They regulate cortisol production, leading to:
- Fewer mood swings and anxiety episodes
- Better emotional control
- Improved mental clarity and calmness
These herbs also enhance sleep quality, which directly influences mood and hormonal balance.
4. Improving Sleep and Energy Levels
Many menopause supplements include magnesium, vitamin B6, and melatonin to help combat insomnia and fatigue.
Better sleep supports:
- Balanced appetite hormones
- Improved mood and focus
- Healthier metabolic function
When your sleep improves, your body can recover, maintain energy levels, and regulate hormones naturally.
5. Strengthening Overall Hormonal Health
A complete menopause supplement often includes a combination of:
- B-complex vitamins – support energy metabolism and nerve function
- Calcium & Vitamin D – maintain bone and muscle health
- Omega-3 fatty acids – reduce inflammation and improve mood
These nutrients work together to keep your body in harmony, reduce stress, and help you feel balanced through menopause.
Best Menopause Supplements for Weight Gain & Mood Swings (2025 List)
Below are the top-rated menopause supplements that help women manage weight gain, mood swings, and hormonal changes naturally. These formulas are known for their effective ingredients, positive results, and safety.
1. Estroven Weight Management
Overview:
Estroven Weight Management is one of the most popular menopause supplements designed to help control weight while supporting hormone balance. It combines plant-based ingredients that naturally mimic estrogen activity, helping reduce hot flashes, irritability, and belly fat caused by hormonal changes.
Key Benefits:
- Supports metabolism and helps reduce abdominal weight
- Balances estrogen levels for improved mood and energy
- Reduces hot flashes, night sweats, and fatigue
- Hormone-free and suitable for long-term use
Ideal For:
Women experiencing weight gain around the midsection and frequent mood swings during menopause.
2. Bonafide Serenol
Overview:
Bonafide Serenol focuses on relieving emotional symptoms of menopause such as anxiety, irritability, and mood fluctuations. It also supports appetite control, which can help prevent unnecessary weight gain during hormonal transition.
Key Benefits:
- Promotes emotional stability and calmness
- Reduces stress-related eating habits
- Helps maintain appetite balance
- Hormone-free and made from natural plant extracts
Ideal For:
Women who experience mood swings, anxiety, and increased appetite during menopause and prefer a gentle, non-hormonal supplement.
3. New Chapter Estrotone
Overview:
New Chapter Estrotone is a herbal supplement that helps support hormonal balance naturally. It combines key herbs that improve mood, energy, and metabolism while reducing common menopause symptoms like bloating and sleep disruption.
Key Benefits:
- Supports hormonal balance and energy levels
- Helps reduce mood swings and mild irritability
- Aids digestion and promotes healthy metabolism
- 100% vegetarian and plant-based
Ideal For:
Women looking for a natural, herbal option that supports overall menopause health, including mood, sleep, and hormone regulation.
Key Ingredients That Support Hormonal Balance and Weight
The most effective menopause supplements work because of their natural ingredients that support the body’s hormonal and metabolic functions. Below are some of the best ingredients to look for when choosing a supplement for weight gain and mood swings.

1. Black Cohosh
Black Cohosh is one of the most trusted herbal ingredients for menopause. It helps reduce hot flashes, night sweats, and mood fluctuations by naturally supporting estrogen balance. Regular use can also improve sleep quality and overall emotional well-being.
2. Soy Isoflavones
Soy isoflavones are plant-based compounds that act like natural estrogen. They help balance hormone levels, reduce irritability, and may assist in controlling menopause-related weight gain. These compounds also promote bone and heart health, which are important during post-menopause.
3. Maca Root
Maca root is known for boosting energy, metabolism, and mood. It helps reduce fatigue and supports better hormonal balance. Many women find it helpful for improving focus, reducing stress, and maintaining a stable weight during menopause.
4. Ashwagandha
Ashwagandha is an adaptogenic herb that helps the body cope with stress. It lowers cortisol levels — the stress hormone linked to fat storage and mood swings. It can also improve sleep and mental clarity, making it one of the best herbs for menopause support.
5. Red Clover
Red Clover contains natural phytoestrogens that help relieve symptoms caused by low estrogen, such as mood changes, hot flashes, and weight gain. It’s gentle, safe, and supports long-term hormonal balance.
6. Green Tea Extract
Green tea extract supports healthy metabolism and helps burn fat more efficiently. It also has natural antioxidants that fight inflammation and boost energy levels. For many women, it’s a key ingredient for maintaining a healthy weight during menopause.
7. B Vitamins and Magnesium
B vitamins and magnesium work together to boost energy metabolism and reduce stress. They also help improve mood, lower fatigue, and promote better sleep quality. Many top menopause supplements include these nutrients to support overall hormonal health.
8. Evening Primrose Oil
Evening Primrose Oil is rich in gamma-linolenic acid (GLA), a fatty acid that helps regulate hormones and improve skin and mood. It’s especially helpful for women experiencing irritability, bloating, or menstrual-like discomfort during menopause.
How to Choose the Right Menopause Supplement
Choosing the right supplement for menopause—especially when dealing with weight gain and mood swings—can feel overwhelming. Here’s a simple, step-by-step guide to help you make a smart and safe decision.
1. Know Your Primary Goal
Start by asking yourself: what symptom bothers me the most?
- Is it weight gain around your abdomen, belly fat, or a slower metabolism?
- Or is it more about mood swings, irritability, sleep problems or low energy?
Pick a supplement whose main benefits match your biggest challenge.
2. Look at the Ingredients & Dosage
Check the label for clarity:
- The ingredients should be clearly listed with amounts (e.g., in mg or mcg).
- Look for well-known active herbs and nutrients, e.g., phyto-estrogens, adaptogens, B-vitamins, magnesium.
- A good supplement should reflect doses that are used in solid research (so you’re not paying for a product with tiny, ineffective amounts).
3. Quality Matters
Not all supplements are created equal. Keep these quality checks in mind:
- Check if the product is from a reputable brand with good reviews.
- Prefer supplements that have third-party testing or transparent quality standards.
- Avoid products that make unrealistic claims like “cure menopause” or “lose 10 kg in 1 month” — these are red flags.
4. Safety & Interactions
Even natural supplements can matter:
- If you have existing conditions (e.g., liver or thyroid issues), or take prescription medications, always check for potential interactions.
- If you have had hormone-sensitive conditions (e.g., breast cancer), consult your doctor especially if a product uses strong phyto-estrogens.
- Start with the lowest recommended dose and monitor how you feel.
5. Consider Your Lifestyle & Budget
A supplement can help—but it works best when combined with supportive lifestyle habits:
- Regular exercise (especially strength training helps with metabolism)
- A balanced diet (lean proteins, vegetables, healthy fats)
- Good sleep and stress-management
Also, consider cost — what you pay is part of your commitment to follow through.
6. Be Realistic About Results & Timing
Supplements are support tools, not miracle fixes.
- Improvements may take 4-12 weeks to show results.
- You might see modest changes in mood stability, mild reduction in belly fat, better sleep — great, but don’t expect overnight dramatic transformations.
- Track your progress by noting changes in mood, energy, weight, sleep quality and overall wellbeing.
7. Re-Evaluate After 3-4 Months
After a few months:
- Ask yourself: “Am I seeing improvements?”
- If not much has changed, it might be time to switch products, adjust lifestyle habits, or consult a healthcare provider.
- If you feel better, you may choose to continue or reduce dose (as advised) and keep monitoring.
Lifestyle Tips to Enhance Supplement Results
While menopause supplements can provide noticeable relief, they work best when combined with a few simple lifestyle changes. A balanced approach will help you manage weight gain, mood swings, and hormonal changes more effectively.

Here are the most important lifestyle habits to focus on:
1. Follow a Balanced, Whole-Food Diet
During menopause, your body needs more nutrients and fewer processed calories. Focus on eating foods that stabilize blood sugar and support hormone balance.
- Include lean proteins like eggs, tofu, and fish to maintain muscle mass.
- Eat plenty of vegetables, fruits, and whole grains for fiber and vitamins.
- Add healthy fats such as olive oil, nuts, and avocados to support hormone production.
- Avoid excess sugar, processed snacks, and fried foods that slow metabolism.
A diet rich in whole foods can prevent sudden weight gain and improve overall mood.
2. Stay Physically Active
Exercise is one of the best natural ways to control menopause symptoms.
- Strength training helps prevent muscle loss and supports metabolism.
- Walking or light cardio improves heart health and burns calories.
- Yoga and stretching reduce stress and improve flexibility.
Aim for at least 30 minutes of activity, five days a week. It also helps your supplements work better by improving nutrient absorption and circulation.
3. Prioritize Sleep
Lack of sleep can increase cortisol levels, making weight loss harder and mood swings worse.
- Try to get 7–8 hours of sleep every night.
- Keep a consistent bedtime and avoid screens an hour before sleeping.
- Create a cool, dark sleeping environment to reduce night sweats and restlessness.
Better sleep improves your emotional balance and metabolism.
4. Manage Stress Effectively
High stress levels trigger cortisol, which promotes fat storage around the belly and increases irritability.
To manage stress naturally:
- Practice deep breathing or meditation for 10–15 minutes daily.
- Try relaxing activities like reading, nature walks, or listening to calming music.
- Limit caffeine and alcohol, which can worsen anxiety and sleep issues.
Combining your supplement routine with stress control leads to steadier mood and weight management.
5. Stay Hydrated
Dehydration can make fatigue, headaches, and mood swings worse.
Drink at least 8–10 glasses of water daily to support digestion, skin health, and energy. Adding lemon or herbal tea can make it more enjoyable.
6. Track Your Progress
Keep a simple daily or weekly record of:
- Energy levels
- Sleep quality
- Mood and stress levels
- Weight or waist changes
This helps you notice what’s working and adjust your supplement or habits accordingly.
7. Avoid Skipping Meals
Skipping meals can cause low blood sugar, leading to irritability and overeating later in the day.
Instead, eat small, balanced meals every 3–4 hours to keep energy steady and prevent hormonal crashes.
Frequently Asked Questions (FAQ)
1. What is the best menopause supplement for weight gain?
The best menopause supplement for weight gain is one that helps balance hormones and supports metabolism. Estroven Weight Management is a popular choice because it includes natural ingredients like soy isoflavones and green tea extract that help control abdominal fat and boost energy levels.
2. Can menopause supplements really help with mood swings?
Yes. Many menopause supplements contain adaptogenic herbs such as ashwagandha, maca root, or chaste tree extract. These herbs help reduce stress, calm the nervous system, and balance mood-related hormones. Over time, they can reduce irritability, anxiety, and emotional ups and downs.
3. Are menopause supplements safe to use long term?
Most natural menopause supplements are safe for long-term use when taken as directed. However, you should always check the ingredient list for any allergens or herbs you may be sensitive to. If you have existing health conditions or take medications, consult a healthcare professional before starting any new supplement.
4. How long does it take to see results from menopause supplements?
Results vary depending on the product and individual body chemistry, but most women begin to notice improvements within 4 to 8 weeks of consistent use. For best results, pair the supplement with a balanced diet, regular exercise, and proper sleep.
5. Do menopause supplements cause weight loss?
Supplements alone won’t cause dramatic weight loss, but they can support fat metabolism and hormone balance. When combined with healthy eating and physical activity, they can help prevent menopause-related weight gain and promote a more stable metabolism.
6. Can I take more than one menopause supplement at a time?
It’s best to take only one well-formulated menopause supplement at a time. Combining multiple products can lead to overlapping ingredients or excess dosages. Choose one complete formula that addresses your main symptoms instead of mixing several products.
7. What vitamins are best for menopause mood and energy?
B-complex vitamins, magnesium, vitamin D, and omega-3 fatty acids are great for boosting mood and energy levels during menopause. They support brain health, reduce fatigue, and help regulate stress hormones.
8. Are there any side effects of menopause supplements?
Most women tolerate menopause supplements well. Minor side effects like mild digestive upset or headaches can occur initially as your body adjusts. Always follow the recommended dosage and take supplements with food to minimize discomfort.
9. Can lifestyle changes replace menopause supplements?
Lifestyle changes such as regular exercise, stress management, and healthy eating can significantly reduce menopause symptoms. However, supplements can provide additional support, especially when hormone fluctuations are strong and natural remedies alone aren’t enough.
10. When should I start taking menopause supplements?
You can start taking menopause supplements during perimenopause — the stage before menopause — when symptoms like irregular periods, mood swings, and sleep problems begin. Early support helps ease the transition and prevents sudden hormonal imbalances.
Conclusion: Find the Best Menopause Supplement for Weight Gain and Mood Swings
Menopause can be a challenging stage of life, but with the right approach, it doesn’t have to disrupt your confidence or comfort. The key lies in maintaining hormonal balance, supporting metabolism, and stabilizing your mood naturally.
The best menopause supplements for weight gain and mood swings combine essential herbs, vitamins, and adaptogens that work together to help your body regain balance. Products like Estroven Weight Management, Bonafide Serenol, and New Chapter Estrotone offer targeted support for the most common menopause symptoms — from stubborn belly fat to emotional ups and downs.
While supplements can make a significant difference, remember that consistency matters. Pairing them with a healthy diet, daily activity, and stress management will deliver the best long-term results.
Every woman’s body is different. Some notice changes within a few weeks, while others take a few months to feel the full benefits. The goal isn’t a quick fix — it’s long-term balance, energy, and peace of mind.
If you’re ready to take control of your health and feel like yourself again, now is the perfect time to start. Choose a trusted, natural supplement that aligns with your goals and begin your journey toward a more comfortable and confident menopause experience.
